carbamyl phosphate การใช้

• Furthermore, carbamyl phosphate prevented the atrophy of the parotid glands associated with the ingestion of sucrose.
• The injection of carbamyl phosphate significantly reversed the effect of sucrose but only in intact rats.
• Carbamyl phosphate, however, was ineffective in parotidectomized rats.
• Therefore, an intact hypothalamic-parotid gland endocrine axis was found to be necessary for the effectiveness of carbamyl phosphate.
• That work involved the discovery of carbamyl phosphate, one compound in the sequence by which nucleotides are made.
• Not surprisingly, intact rats fed carbamyl phosphate along with a cariogenic diet showed a highly significant reduction in caries.
• Then it was found that the sucrose effect could be effectively reversed by the infusion of the compound carbamyl phosphate through the internal carotid artery.
• She and Spector continued to work on carbamyl phosphate, identifying carbon dioxide or bicarbonate as the source for the initial activation step for carbamyl phosphate formation.
• She and Spector continued to work on carbamyl phosphate, identifying carbon dioxide or bicarbonate as the source for the initial activation step for carbamyl phosphate formation.